Clonaid Totally Explained

Everything about Clonaid totally explained

Clonaid is a human cloning company founded in 1997. It has philosophical ties with the Raëlian sect, which sees cloning as the first step in achieving immortality. On December 27 2002, Clonaid's chief executive, Brigitte Boisselier, claimed that a baby clone, named Eve, was born. Media coverage of the claim sparked serious criticism and ethical debate that lasted more than a year. Florida attorney Bernard Siegel tried to appoint a special guardian for Eve and threatened to sue Clonaid, because he was afraid that the child might be treated like a lab rat. Siegel, who heard the company's actual name wasn't Clonaid, decided that the Clonaid project was a sham. Scientists in the field condemned Clonaid for premature human experimentation and noted the high incidence of malformations and fetal deaths in animal cloning.
On June 15, 1998, Brigitte Boisselier said the headquarters of Clonaid was located in Las Vegas, Nevada and that Clonaid didn't have enough funds for human cloning research. In December 19, 1998, a New Scientist article said the cost of Clonaid cloning services would be $200,000, lower than the $2.3 million dollars that researchers at Texas A&M University planned to use for cloning a dog named Missy. Mainstreams scientists said it was unlikely that Clonaid would be able to clone anything in the near future. Although the project's ultimate objective was human cloning, she said that pet cloning would help finance the operations.
Claude Vorilhon held a meeting in a Montreal hotel on September 21, 2000, where he announced that a wealthy American couple was willing to fund the Clonaid project. The first pending clone, according to Vorilhon at the time, was an American couple's 10-month old girl, who died due to a medical mistake. He said that the couple was willing to pay $500,000 to clone their deceased daughter, but the wife wasn't willing to be the surrogate mother. Jamie Grifo, a fertility specialist at the New York University School of Medicine and Nobel laureate Paul Berg of Stanford University said that Vorilhon was providing a false hope that the child was going to be the same one. Boisselier revealed the roles of four scientists she says were involved—"a biochemist, a geneticist, a cell fusion expert, and a French medical doctor"—but without revealing their identity. She didn't identify the wealthy American couple.

Responses by scientists

According to cloning specialist and physiologist George Seidel of Colorado State University, cloning a human being wouldn't be difficult if many people donated their eggs or offered their wombs for implantation of clone embryos. Lee Silver, a molecular biologist from Princeton, noted the advantages that Raëlians had, as a pro-cloning religious group, in finding willing surrogates. A biotechnology company called Advanced Cell Technology had cloned human embryo cells for medical purposes, and its CEO Michael West said that the directions for cloning a human being were available in published scientific literature. Some experts noted that scientists understood human reproductive chemistry better than that of most animals. For this reason, they thought that a higher rate of success was possible in human cloning compared with animal cloning. Brigitte Boisselier anticipated that the work could begin on the preserved cells as soon as October, but there was no evidence that Clonaid had medical knowledge necessary for its success. There was no evidence that the Clonaid claim was a more than a publicity stunt. the Food and Drug Administration Office of Criminal Investigations investigated Clonaid's lab in Nitro, West Virginia. It was located inside a rented room within an abandoned high school. Staff scientists reviewed the books in the lab and found them to be sketchy—thus they didn't adequately document scientific research. Apparently, it was the work of a graduate student who was working on cow ovaries from a slaughterhouse in order to extract ovaries from them. The FDA said that the equipment in lab was state-of-the-art and had been bought by a former West Virginia state legislator Mark Hunt who wanted to clone his 10-month old dead son, Andrew, who died in 1999 due to congenital heart disease. Following investigation of the West Virginia lab, Mark Hunt made an agreement with the FDA-OCI to not clone his dead son within the United States.
On March 2001, Boisselier said that a woman would be pregnant with a cloned fetus in April. She said that cells had reached the blastocyst stage, but she refused to speak of any specific implantation or pregnancy associated with them. According to a CNN article that November, the Clonaid laboratory was outside the United States. Clonaid claimed that it had developed human cloned embryos before Advanced Cell Technology was able to do the same. CNN couldn't confirm the unpublished work. Due to Clonaid's association with Raëlians and the lack of evidence for cloning, authorities remained skeptical as to whether Clonaid could clone anything at all.

Alleged clone baby Eve

On Friday December 27, 2002, Boisselier, a Raëlian bishop and CEO of Clonaid, announced at press conference in Hollywood, Florida that Clonaid had successfully performed the first human reproductive cloning. Boisselier said that the mother delivered Eve by Caesarean section somewhere outside the United States and that both were healthy. Dr. Boisselier didn't present the mother or child, or DNA samples that would allow for confirmation of her claim at the press conference. It has subsequently become apparent that she announced the birth before genetic testing to evaluate whether the child in question is actually a clone: Dr. Boisselier was therefore stating her belief that her procedure had resulted in a clone, not announcing results showing that the child was a clone.
Shortly after the announcement, Korean prosecutors raided the offices of Clonaid's Korean branch, BioFusion Tech. In the process, the prosecutors removed records from homes and offices while barring two representatives of BioFusion Tech from leaving the country. An official company statement revealed that three Korean women applied to become surrogate mothers. Officials of BioFusion Tech told the prosecutors that 10 Korean women wanted to clone themselves and have filled out applications.
The Food and Drug Administration stated its intention to investigate Clonaid to see if it had done anything illegal. The FDA contended that its regulations forbid human cloning without prior agency permission. However, some members of the United States Congress believed that the jurisdiction of the FDA on human cloning matters was shaky and decided to push Congress to explicitly ban human cloning.

Responses by politicians and ethicists

President George W. Bush said that human cloning was "deeply troubling" to most Americans. Kansas Republican Sam Brownback said that Congress should ban all human cloning, while some Democrats were worried that Clonaid announcement would lead to the banning of therapeutic cloning. FDA biotechnology chief Dr. Phil Noguchi warned that the human cloning, even if it worked, risked transferring sexually transmitted diseases to the newly born child. University of Wisconsin-Madison bioethicist Alta Charo said that even in other ape-like mammals, the risk for miscarriage, birth defects, and life problems remains high. Robert Lanza of Advanced Cell Technologies said that Clonaid has no record of accomplishment for cloning anything, but he said that if Clonaid actually succeeded, there would be public unrest that may lead to the banning of therapeutic cloning, which has the capacity to cure millions of patients. The Vatican said that the claims expressed a mentality that was brutal and lacked ethical consideration. The White House was also critical of the claims. but Florida attorney Bernard Siegel filed a petition as a private citizen in the Broward County Circuit Court requesting that a temporary guardian be appointed for the purported cloned child. As the court case played out over the next month, Dr. Boisselier testified under oath that there was a cloned child, born in Israel. However, Clonaid didn't present demonstrative evidence that the child really existed. Boisselier said that Eve would travel to the United States that day for DNA tests. She said that a pediatrician saw Eve and her mother in good condition, but she refused to mention the location of the surrogate birth, the testing lab, or the biological mother's home, which she wanted to reveal at a later time. The mother was said to be 31 years old with an infertile husband.

Request for a DNA verification test

Michael Guillen, a former ABC News science editor, made an agreement with Boisselier for him to choose independent experts to test for a DNA match. Clonaid refused to identify the independent experts, because if revealed too soon, others could track the baby from the testing place into the mother's house. Clonaid said the parents had the final say on whether they want to test the baby and that a Dutch lesbian couple would be the parents of the next cloned baby. Boisselier said she'd hand over the evidence to show that a clone had in fact been born but was concerned that the details of Clonaid's cloning procedure might leak out.
Thomas Kaenzig refused to testify in a court hearing, but Florida judge John Frusciante was able to convince Kaenzig through a telephone to reveal some of the details. Kaenzig testified that Clonaid left him ignorant of the cloning project and that it wasn't even a corporation. The judge summoned Kaenzig and Brigitte Boisselier to a Florida court and warned the two that they'd be condemned if they didn't show there on January 29, 2003. As the court case played out, Dr. Boisselier testified under oath that she saw videos of a cloned child born in Israel.
Michael Guillen was disappointed when he discovered that Clonaid withdrew their offer to provide the tests. The company said that before the tests were done, the parents wanted to be sure that their baby wouldn't be sent away, but a Florida attorney asked that a guardian for Eve be appointed and threatened the company with a lawsuit. Guillen, who remained skeptical, said it would be unwise to dismiss the Clonaid project without proper confirmation.

Claims of further human clones

The day after Boisselier made her announcement, she added that four more human clones were to be born within a few weeks. Boisselier claimed that Clonaid had a list of couples who were ready to have a cloned child. On January 5, 2003, Brigitte Boisselier said to the BBC that her medical team produced hundreds of human clone embryos before proceeding to ten implantations, two of which led to births. The head of the UK Roslin Institute was critical of the assertion, "Clonaid [has] no track record but claim[s] to have cloned hundreds of embryos - it just doesn't ring true."
   A Raëlian spokeswoman from Japan claimed that a baby boy, cloned from a comatose two year-old of a Japanese couple, was born the previous day. Boisselier said that a surrogate participated since the biological mother was 41 and more likely to have a miscarriage. Scientists knew that many cloned animals suffer arthritis and ailments with the lungs and liver, and they were concerned that too many unanswered questions surround the prospect of cloning of humans safely. Clonaid set up press conferences in which they described their method of cloning, but they didn't give any details. However, they did say that the third cloning was different, in that didn't involve a mothers egg, but the surrogate's egg with the injection of the boy's DNA.
   According to Boisselier, Mark and Tracy Hunt, who were seeking clone their dead son, invested $500,000 in the former Clonaid lab in West Virginia and its equipment, which the Food and Drug Administration shut down. The Clonaid CEO proposed a cloning lab on Brazilian island for creating the next generation of clone babies.
   In late July 2002, Clonaid's branch in South Korea, BioFusion Tech, said a woman became pregnant with a human clone. However, in the week of September 27, 2002, South Korea's Ministry of Health and Welfare in Korea announced that it would ban human cloning and sentence violators to a 10-year prison term. Branch spokesman Kwak Gi-Hwa said that the surrogate mother, unmarried at 26 years old, moved out of South Korea into another country. The spokesman said he'd no knowledge of which country that was and that only a few people in Clonaid knew. He described himself as simply a volunteer for the branch which had closed under government pressure following their claim. He accused the government of Korea of considering Christian opinions of human cloning over those of scientists who criticized the proposed human cloning ban. He was later summoned to witness in front of the Korean Parliament.
   In February 2004, Clonaid claimed that a sixth clone baby was born in Australia. Additionally, it claimed to have produced human embryos in South Korea. The small number of companies that have access to cloning technology has resulted skepticism by cloning experts in Korea, who accused Clonaid of defaming the now debunked stem cell work of Doctor Hwang Woo-suk. By March 2004, Clonaid claimed that eight extra baby clones had been brought to term for a total of thirteen baby clones.

Embyronic cell fusion machine

Besides offering cloning services, Clonaid has developed one product, an "embryonic cell fusion device" called the RMX 2010.
CNN Money has listed the RMX 2010 as the fourth "Dumbest Moment in Business 2003", stating "Clonaid sells the RMX 2010, a $9,220 contraption that ... well, nobody's quite sure what it does. To help clarify the matter, Clonaid lends one to a British science museum—under strict orders not to open it to find out what's inside."

Additional skepticism

Scientists interviewed about the announcement averred skepticism regarding both the authenticity and the ethics of Clonaid's procedures. These included Lord Robert Winston, head of the IVF research team at London's Hammersmith Hospital, and Tanja Dominko of the Oregon Regional Primate Center's monkey cloning project. Scientists with experience in animal cloning have encountered low rates of success per implantation, where cloned fetuses are often malformed and dead before birth. Regardless, people continue to be surprised that Clonaid appears to have overcome those problems; either Clonaid has been extremely lucky in discovering a superior method of cloning, or the company is making false claims.
Clonaid charges up to $200,000 for its "cloning" services. According to sealed court documents received by the Boston Globe which were reported on April 27, 2003, Clonaid had two employees but no address or board of directors. CBS News reported that Clonaid wasn't a company. Boisselier revealed that in a strict sense, Clonaid was just the product name, even though Clonaid's website had touted it as the company name.

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